Biological products refer to drugs prepared from microbial, cellular, and various animal and human tissues and fluids obtained through biotechnology such as genetic engineering, cell engineering, protein engineering, and fermentation engineering, and are used for the prevention, treatment, and diagnosis of human diseases.Because biological products need to go through multiple biological processes and purification processes to remove impurities in order to obtain the desired products, biological products have extremely complex uncertainties at every step. The quality control of biological products throughout the entire process has strict requirements, so filtration is crucial for process control. Take vaccines as an example.
Vaccines are preventive biologics used for human immunization to prevent and control the occurrence and spread of infectious diseases. The principle behind vaccines is to use artificially attenuated, inactivated, or genetically modified pathogenic microorganisms (such as bacteria, rickettsiae, viruses, etc.) and their metabolites to produce automatic immunizing agents for preventing infectious diseases. Currently, the majority of vaccines used are for preventing viral or bacterial infections, and they are mainly categorized as inactivated vaccines, live attenuated vaccines, toxoids, subunit vaccines, polysaccharide vaccines, nucleic acid vaccines (DNA vaccines and RNA vaccines), etc.
Workstation | Function | Recommended Filter Cartridge Series | Recommended Filter Housing Series |
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1 Culture medium filtration | Remove bacteria and microorganisms from cell culture medium. |
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2 Gas and respirator | Removal of bacteria and other microorganisms in gases. |
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3 Clarification filtration | Removal of dead cells, cell fragments, lipids, colloids, particles, and other impurities. |
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4 Security filtration | Pre-filtration before UF to protect the UF module. |
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6 Buffer solution filtration | Sterilization filtration of buffer solutions to extend the lifespan of chromatography columns and UF membranes. |
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7 Terminal sterilizing filter | Remove bacteria and microorganisms from terminal filtrate. |
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